3e:null 3f:["$","title",null,{"children":"PK/PD Simulator Playground | JR | Observable"}] 45:T110a,final_chart = { const viewWidth = width; const maxWidth = 900; const viewHeight = 600; // const viewHeight=520 const margin = { top: 50, bottom: 10, left: 0, right: 40 }; //const final = state.doses + state.infusion; const Streams = dosesToStreams(sumMap, { totalHours, Bolus //sumMap, //infusion }).sort((l, r) => l[0][0] - r[0][0]); // const Streams_2 = dosesToStreams(state.infusion, { // totalHours, // Bolus // }).sort((l, r) => l[0][0] - r[0][0]); const stackedStreams = stackStreams(Streams); //const stackedStreams = stackStreams(combined_array_2); let streamsToPlot = stackedStreams.map((curStream) => { return curStream .filter(([x]) => x <= totalHours) .map(([x, y0, y]) => ({ x, y0, y })); }); // Assign IDs to the streams let streamCountByTime = new Map(); streamsToPlot.forEach((curStream) => { const countForTime = streamCountByTime.get(curStream[0].x) || 0; // Update streamCountByTime streamCountByTime.set(curStream[0].x, countForTime + 1); // Set an ID on the current stream curStream.id = `${curStream[0].x}_${countForTime}`; }); const streamIDs = new Set(streamsToPlot.map((ds) => ds.id)); const enteredStreamIDs = new Set( [...streamIDs].filter((x) => !visibleStreamIDs.has(x)) ); const exitedStreamIDs = new Set( [...visibleStreamIDs].filter((x) => !streamIDs.has(x)) ); if (0 !== enteredStreamIDs.size || 0 !== exitedStreamIDs.size) { // mutable visibleDataHashes = dataHashes console.log("Entered: " + Array.from(enteredStreamIDs)); console.log("Exited: " + Array.from(exitedStreamIDs)); new Promise(async () => { await Promises.delay(500); mutable visibleStreamIDs = new Set( [...visibleStreamIDs, ...enteredStreamIDs].filter( (x) => !exitedStreamIDs.has(x) ) ); }); } // Mark new streams as entered // This is not great and super fragile streamsToPlot.forEach((curStream) => { curStream.entered = enteredStreamIDs.has(curStream.id); curStream.exited = exitedStreamIDs.has(curStream.id); }); // return streamsToPlot const maxThreshold = d3.max( streamsToPlot.flat().map((d) => TargetThreshold <= d.y) ); const BelowTargetThreshold = maxThreshold <= TargetThreshold; const calculateTime = calculatecalculateTime(streamsToPlot); // const description = getDescriptionText(streamsToPlot); // const descriptionParts = description.split("\n"); const colors = d3.quantize( d3.interpolateRgb("#FBD871", "#5CC1E7"), Math.max(3, streamsToPlot.length) ); // const grid = renderGrid() const grid = null; const renderedfinalChart = finalChart(streamsToPlot, { colors, width: viewWidth - margin.left - margin.right, height: viewHeight - margin.top - margin.bottom, domain: [0, totalHours - 1] }); return svg` `; }46:T5b9,renderInputter = (doses, onChange, params) => { params = params || {}; const width = params["width"] || 800; // Determine the hours users can set const hoursToPlot = d3.range(0, totalHours, 1); const colCount = 320 < width ? totalHours / 12 : 1; const hoursPerCol = Math.floor(hoursToPlot.length / colCount); const output = html`

${d3.range(colCount).map((colIndex) => { const hours = hoursToPlot.slice( colIndex * hoursPerCol, (colIndex + 1) * hoursPerCol ); return html`

Day = ${Math.floor(colIndex / 2 + 1)} ${hours.map((k) => { const row = html` `; row[`${k}-inc`].disabled = 10 <= doses.get(k); row[`${k}-dec`].disabled = !doses.get(k) || doses.get(k) <= 0; row[`${k}-inc`].addEventListener("click", () => { onChange(k, 1); }); row[`${k}-dec`].addEventListener("click", () => { onChange(k, -1); }); return row; })}

`; })}

`; return output; }47:T618,/** * Render a controller for adding / subtracting simulated coffee */ renderCoffeeInputter_infusion = (infusion, onChange_infusion, params) => { params = params || {}; const width = params["width"] || 800; // Determine the hours users can set const hoursToPlot = d3.range(0, totalHours, 1); const colCount = 320 < width ? totalHours / 12 : 1; const hoursPerCol = Math.floor(hoursToPlot.length / colCount); const output = html`

${d3.range(colCount).map((colIndex) => { const hours = hoursToPlot.slice( colIndex * hoursPerCol, (colIndex + 1) * hoursPerCol ); return html`

${hours.map((k) => { const row = html` `; row[`${k}-inc`].disabled = 5 <= infusion.get(k); row[`${k}-dec`].disabled = !infusion.get(k) || infusion.get(k) <= 0; row[`${k}-inc`].addEventListener("click", () => { onChange_infusion(k, 0.5); }); row[`${k}-dec`].addEventListener("click", () => { onChange_infusion(k, -0.5); }); return row; })}

`; })}

`; return output; }48:T8fa,finalChart = (data, params) => { params = params || {}; let colors = params["colors"] || []; // Plot fn const plotFn = (data, params) => { return shakyStreamPlotFn(data, { ...params, colors }); }; // Plot fn for the overlaid cups and sleep line const contextPlotFn = (seriesData, params) => { const { x, y, seriesIndex } = params; // Only render this once if (seriesIndex !== 0) return null; const cups = svg` ${cupsPlotFn(data, params)} `; const sleepLine = sleeplinePlotFn(data, { ...params, TargetThreshold }); const sleepThresholdLine = svg``; const dayNightBar = svg` ${renderDayNightBar()}`; const tox_range_level = svg` ${rendertox_range_level()} `; const therapeutic_range_level = svg` ${rendertherapeutic_range_level()} `; return svg` ${cups} ${dayNightBar} ${tox_range_level} ${therapeutic_range_level} `; }; //${sleepLine} // Determine the largest number of coffee cups being rendered // to calculate how much to offset the margin let maxCupCount = d3.max( Array.from( d3.rollup( data.map((d) => d[0].x), (xs) => xs.length, (x) => x ) ).map(([_, v]) => v) ); maxCupCount = maxCupCount || 1; params = { plotFn, contextPlotFn, margin: { top: 15, left: 140, right: 36, bottom: 60 + 20 * maxCupCount }, xAxisTickSizeInner: 10, // Set a minimum range, so it feels less jarring w/ few drinks added range: [ Math.min(0, d3.min(data.flat().map((d) => d.y))), Math.max(12, Math.ceil(d3.max(data.flat().map((d) => d.y)) / 100.0) * 100) ], xTickFormatFn: hourToTimeString, yTickFormatFn: (n) => n + " mcg/mL", ...params }; return chart(data, params); }49:Tb67,/** * chart boilerplate. */ chart = (stackedData, params) => { params = params || {}; const width = params["width"] || 320; const height = params["height"] || 120; const color = params["color"] || "#004479"; const classId = params["class"] || ""; const xAxisTickSizeInner = params["xAxisTickSizeInner"] || 3; const domain = params["domain"] || [ d3.min(stackedData.flat().map((d) => d.x)), d3.max(stackedData.flat().map((d) => d.x)) ]; const range = params["range"] || [ Math.min(0, d3.min(stackedData.flat().map((d) => d.y))), d3.max(stackedData.flat().map((d) => d.y)) ]; const yMax = range[1]; const yMin = range[0]; const xTickFormatFn = params.xTickFormatFn || d3.format(".1d"); const yTickFormatFn = params.yTickFormatFn || d3.format(".1d"); let margin = { top: 10, right: 0, bottom: 24, left: 100, spacing: 1, ...(params.margin || {}) }; const plotHeight = height - margin.top - margin.bottom; const plotWidth = width - margin.left - margin.right; const plotFn = params["plotFn"] || ((data, params) => {}); const contextPlotFn = params["contextPlotFn"] || ((data, params) => {}); const x = d3.scaleLinear().domain(domain).range([0, plotWidth]); const axisBottom = d3.axisBottom(x).tickFormat(xTickFormatFn); const xAxis = (g) => g .attr("class", `x-axis`) .attr("transform", `translate(0,${plotHeight})`) .call(axisBottom.tickSizeOuter(1).tickSizeInner(xAxisTickSizeInner)); const y = d3.scaleLinear().domain(range).range([plotHeight, 0]); const axisLeft = d3.axisLeft(y).tickFormat(yTickFormatFn); const yAxis = (g) => g .attr("class", `y-axis`) .attr("transform", `translate(${0},${-3})`) .call(axisLeft.ticks(10).tickSize(0)); // .call(axisLeft) // return html` `; }4a:[] 43:{"id":"f1697b35ac98b8e4","slug":null,"title":"PK/PD Simulator Playground","thumbnail":"f7f546ea67afe72d541c047edbe24854fb9ce988ca1d5cbc5be0d0aa6c4feb1c","access_level":"public","create_time":"$D2023-05-17T07:37:45.821Z","update_time":"$D2023-05-19T01:38:22.488Z","view_time":null,"first_public_time":"$D2023-05-17T07:37:45.821Z","has_unpublished_edits":null,"fork":{"id":"374ed0b4e85350e4","slug":null,"title":"PK/PD Simulator","owner":{"id":"b756b2b38e16dec7","login":"jr15","name":"JR"}},"stars":0,"starred":false,"owner":{"type":"team","id":"b756b2b38e16dec7","login":"jr15","name":"JR","avatar_url":"https://avatars-next.observableusercontent.com/fba3fbbfb4ccec850d4f464fe26ca1861b43dff64a0b0750427d258677281ee7","tier":"starter_2024","bio":"","following":false},"version":5195,"publish_version":null,"role":null,"authored":false,"authors":[{"type":"individual","id":"6f607e7d94e2337a","login":"jr15","name":"JR","avatar_url":"https://avatars-next.observableusercontent.com/fba3fbbfb4ccec850d4f464fe26ca1861b43dff64a0b0750427d258677281ee7","tier":null,"bio":"","following":false}],"members":[{"type":"individual","id":"6f607e7d94e2337a","login":"jr15","name":"JR","avatar_url":"https://avatars-next.observableusercontent.com/fba3fbbfb4ccec850d4f464fe26ca1861b43dff64a0b0750427d258677281ee7","tier":null,"role":"editor"}],"comments":[],"custom_thumbnail":false,"trashed":false,"lapsed":null,"subscribed":null,"forks":0,"collection":null,"type":"notebook","body":{"titling":"auto","title":"PK/PD Simulator Playground","cells":[{"id":0,"value":"md`# PK/PD Simulator Playground`","pinned":false,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":118,"value":"$45","pinned":false,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":4716,"value":"Inputs.button(\n [\n [\n \"Reset\",\n () => [set(viewof totalHours, 24), set((state.doses = new Map([[0, 1]])))]\n ]\n ],\n { width: 200 }\n)","pinned":false,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":3439,"value":"viewof totalHours = Inputs.range([max_hours + 1, 72], {\n label: \"# of hours to evaluate\",\n step: 1,\n value: 24\n})","pinned":false,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":4162,"value":"### Pentbobarbital Bolus","pinned":false,"hidden":false,"mode":"md","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"","database":"$undefined"},{"id":517,"value":"boluses = {\n // Handle updating state whenever one of the buttons are clicked\n const onChange = (k, delta) => {\n // Get doses with the new count applied\n let newDoses = new Map([\n ...state.doses,\n [k, Math.max(0, (state.doses.get(k) || 0) + delta)]\n ]);\n //remove zeros\n newDoses = Array.from(newDoses).filter(([k, v]) => 0 < v);\n //Update state\n mutable state = { ...state, doses: new Map(newDoses) };\n };\n return renderInputter(state.doses, onChange, {});\n}","pinned":false,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":4164,"value":"### Pentbobarbital Infusion","pinned":false,"hidden":false,"mode":"md","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"","database":"$undefined"},{"id":4153,"value":"{\n // PINEAPPLE\n // Handle updating state whenever one of the buttons are clicked\n const onChange_infusion = (k, delta) => {\n // Get doses with the new count applied\n let newInfusion = new Map([\n ...state.infusion,\n [k, Math.max(0, (state.infusion.get(k) || 0) + delta)]\n ]);\n //remove zeros\n newInfusion = Array.from(newInfusion).filter(([k, v]) => 0 < v);\n //Update state\n mutable state = { ...state, infusion: new Map(newInfusion) };\n };\n return renderCoffeeInputter_infusion(state.infusion, onChange_infusion, {\n width: 900\n });\n}","pinned":false,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":4821,"value":"state","pinned":true,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":4879,"value":"bolus_doses = dosesToStreams(state.doses, {\n totalHours,\n Bolus\n //sumMap,\n //infusion\n}).sort((l, r) => l[0][0] - r[0][0])","pinned":true,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":4882,"value":"// sumofBolus_Infusion = [...state.doses.values(), ...bolus_doses].reduce(\n// (accumulator, currentValue) => accumulator + currentValue\n// )","pinned":true,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":4899,"value":"// sumArray = Array.from(\n// state.doses.values(),\n// (value, index) => value + bolus_doses[index]\n// )","pinned":true,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":4296,"value":"state.doses","pinned":true,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":4763,"value":"// sumMap_original = new Map(\n// Array.from(state.doses.keys(), (key) => [\n// key,\n// state.doses.get(key) + (state.infusion.get(key) || 0)\n// ])\n// )","pinned":true,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":4804,"value":"//sumMap = new Map()","pinned":true,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":4768,"value":"sumMap = new Map(\n Array.from(state.doses.keys(), (key) => [\n key,\n (state.doses.get(key) || 0) + (state.infusion.get(key) || 0)\n ])\n)","pinned":true,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":4869,"value":"sumMap1 = new Map(\n Array.from(\n new Set([...state.doses.keys(), ...state.infusion.keys()])\n ).forEach((key) => {\n const sum = (state.doses.get(key) || 0) + (state.infusion.get(key) || 0);\n sumMap.set(key, sum);\n })\n)","pinned":true,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":4809,"value":"(state.total = sumMap)","pinned":true,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":5194,"value":"## last edited below\n","pinned":false,"hidden":false,"mode":"md","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"","database":"$undefined"},{"id":4776,"value":"Streams_2 = infusionToStreams(state.infusion, {\n totalHours,\n //Bolus,\n infusion\n}).sort((l, r) => l[0][0] - r[0][0])","pinned":true,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":5154,"value":"Streams_e = infusionToStreams(state.infusion, {\n totalHours,\n Bolus,\n infusion\n //sumMap,\n //infusion\n}).sort((l, r) => l[0][0] - r[0][0])","pinned":true,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":4839,"value":"Streams_extra = dosesToStreams(state.doses, {\n totalHours,\n Bolus\n // sumMap,\n //infusion\n}).sort((l, r) => l[0][0] - r[0][0])","pinned":true,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":4859,"value":"state.doses","pinned":true,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":4862,"value":"state.infusion","pinned":true,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":4864,"value":"sumMap","pinned":true,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":4731,"value":"#### Figuring out the max serum level and the time of the maximum","pinned":false,"hidden":false,"mode":"md","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"","database":"$undefined"},{"id":4461,"value":"max_hours = {\n if (d3.max(Array.from(state.doses.keys())) === undefined) return 1;\n else return d3.max(Array.from(state.doses.keys()));\n}","pinned":true,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":4577,"value":"Streams = dosesToStreams(state.doses, {\n totalHours,\n Bolus\n //infusion\n}).sort((l, r) => l[0][0] - r[0][0])","pinned":true,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":4928,"value":"Streams_infusion = infusionToStreams(state.infusion, {\n totalHours,\n Bolus\n //infusion\n}).sort((l, r) => l[0][0] - r[0][0])","pinned":true,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":4921,"value":"### take streams and add the value of infusion to it","pinned":false,"hidden":false,"mode":"md","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"","database":"$undefined"},{"id":4936,"value":"// result = Streams.map((arr, index) => arr[1] + Streams_infusion[index][1])","pinned":true,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":4970,"value":"array1 = Streams","pinned":true,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":4972,"value":"array2 = Streams_infusion\n","pinned":true,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":5140,"value":"Streams.push(Streams_infusion)","pinned":true,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":5108,"value":"### i’m here (pineapple)","pinned":false,"hidden":false,"mode":"md","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"","database":"$undefined"},{"id":5111,"value":"summed_array_original = array1.map((item, index) => [\n item[0],\n item[1] + array2[index][3]\n])","pinned":true,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":5122,"value":"[array2.flat()]","pinned":true,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":5050,"value":"array2_2 = [array2]","pinned":true,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":5054,"value":"array1_2 = [array1]","pinned":true,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":4989,"value":"summed_array = array1_2.map((item, index) => [\n item[0],\n item[1] + array2_2[index][1]\n])","pinned":true,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":5061,"value":"combined_array = summed_array.flat().flat()","pinned":true,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":5081,"value":"combined_array_2 = [combined_array]","pinned":false,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":5073,"value":"Streams","pinned":true,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":4997,"value":"result_2 = array1.map((item, index) => {\n const nestedSum = item[2].map(\n (value, nestedIndex) => value + array2[index][2][nestedIndex]\n );\n return [item[1], nestedSum];\n})","pinned":true,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":5015,"value":"#example array","pinned":false,"hidden":false,"mode":"md","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"","database":"$undefined"},{"id":4980,"value":"array = [\n [1, 2],\n [2, 1]\n]","pinned":true,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":4978,"value":"### break","pinned":false,"hidden":false,"mode":"md","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"","database":"$undefined"},{"id":4574,"value":"stackedStreams = stackStreams(Streams)","pinned":false,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":4548,"value":"streamsToPlot = stackedStreams.map((curStream) => {\n return curStream\n .filter(([x]) => x <= totalHours)\n .map(([x, y0, y]) => ({ x, y0, y }));\n})","pinned":false,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":4572,"value":"estimated_serum_level = round(d3.max(streamsToPlot.flat().map((d) => d.y)), 0)","pinned":false,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":4586,"value":"maxIndex = d3.maxIndex(streamsToPlot.flat().map((d) => d.y))","pinned":false,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":4630,"value":"flat_array = streamsToPlot.flat()","pinned":false,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":4615,"value":"max_hour = flat_array[maxIndex].x","pinned":false,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":4659,"value":"formattedHour = max_hour % 24","pinned":false,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":4653,"value":"formattedHour12 = max_hour % 12 || 12","pinned":false,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":4655,"value":"period = formattedHour < 12 ? \"AM\" : \"PM\"","pinned":false,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":4584,"value":"The highest estimated serum level of pentobarbital is **${estimated_serum_level}** achieved at **${formattedHour12} ${period}**.","pinned":false,"hidden":false,"mode":"md","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"","database":"$undefined"},{"id":1602,"value":"md`## Settings`","pinned":false,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":2140,"value":"viewof HalfLifeHrs = {\n const output = slider({\n title: \"Pentobarbital Half-Life (hours)\",\n min: 15,\n max: 50,\n step: 1,\n value: state.HalfLifeHrs || 26,\n description:\n \"Pentobarbital's half-life: 26 hours is typical, but it can range from 15 - 50 hours.\"\n });\n output.addEventListener(\"mouseup\", () => {\n mutable state = { ...state, HalfLifeHrs: parseFloat(output.value) };\n });\n return output;\n}","pinned":false,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":1148,"value":"viewof therapeutic_threshold_input = Inputs.select(\n [\"20 mcg/mL\", \"30 mcg/mL\", \"40 mcg/mL\"],\n { label: \"Therapeutic Threshold (mcg/mL)\", value: \"30 mcg/mL\" }\n)","pinned":false,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":3465,"value":"viewof toxic_threshold_input = Inputs.select(\n [\n \"50 mcg/mL\",\n \"60 mcg/mL\",\n \"70 mcg/mL\",\n \"80 mcg/mL\",\n \"90 mcg/mL\",\n \"100 mcg/mL\"\n ],\n { label: \"Toxic Threshold (mcg/mL)\", value: \"60 mcg/mL\" }\n)","pinned":false,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":3910,"value":"TargetThreshold = {\n if (therapeutic_threshold_input == \"30 mcg/mL\") {\n return 30;\n } else if (therapeutic_threshold_input == \"40 mcg/mL\") {\n return 40;\n } else {\n return 20;\n }\n}","pinned":false,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":3472,"value":"toxic_threshold = {\n if (toxic_threshold_input == \"50 mcg/mL\") {\n return 50;\n } else if (toxic_threshold_input == \"60 mcg/mL\") {\n return 60;\n } else if (toxic_threshold_input == \"70 mcg/mL\") {\n return 70;\n } else if (toxic_threshold_input == \"80 mcg/mL\") {\n return 80;\n } else if (toxic_threshold_input == \"90 mcg/mL\") {\n return 90;\n } else {\n return 100;\n }\n}\n","pinned":false,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":818,"value":"md`## State`","pinned":false,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":4120,"value":"Bolus = 1","pinned":true,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":4178,"value":"infusion = 1","pinned":true,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":654,"value":"mutable state = getInitialStateFromShareURL(location.href) || {\n Bolus: 1,\n HalfLifeHrs: 26,\n TargetThreshold: 30,\n doses: new Map([[0, 1]]),\n infusion: new Map([[0, 1]]),\n total: new Map([[0, 1]])\n}","pinned":false,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":2933,"value":"// To support enter animations w/o giving up declarative svg\nmutable visibleStreamIDs= new Set()","pinned":false,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":2927,"value":"md`---`","pinned":false,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":777,"value":"md`## Utils`","pinned":false,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":703,"value":"createShareURL = (currentURL, state) => {\n if (!state) return currentURL;\n const [baseURL, queryString] = currentURL.split(\"?\");\n const preparedState = {\n ...state,\n doses: Object.fromEntries(state.doses),\n infusion: Object.fromEntries(state.infusion)\n };\n const queryParams = new URLSearchParams(queryString);\n queryParams.set(\"state\", btoa(JSON.stringify(preparedState)));\n return baseURL + \"?\" + queryParams.toString();\n}","pinned":false,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":725,"value":"getInitialStateFromShareURL = (url) => {\n if (!url) return null;\n\n const queryParams = new URLSearchParams(url.split(\"?\")[1]);\n\n if (!queryParams.get(\"state\")) return null;\n\n try {\n let output = JSON.parse(atob(queryParams.get(\"state\")));\n output = {\n ...output,\n doses: new Map(\n Object.entries(output.doses).map(([k, v]) => [parseInt(k), v])\n ),\n infusion: new Map(\n Object.entries(output.infusion).map(([k, v]) => [parseInt(k), v])\n )\n };\n return output;\n } catch (ex) {\n return null;\n }\n}","pinned":false,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":449,"value":"//This is kindof a stupid design\nupsample= (data, keys, multiple=10) => {\n const interpolators = keys.map(k=>(data.map(d=>d[k])))\n .map(x=>(d3.piecewise(d3.interpolateNumber, x)))\n // .map(d3.interpolateBasis)\n const n = data.length * multiple\n \n const upsampledData = interpolators\n .map(interpolator=> d3.quantize(interpolator, n))\n \n return d3.range(n).map(i=>{\n return keys.reduce((agg,k,j)=>({...agg, [k]: upsampledData[j][i]}),{})\n })\n}","pinned":false,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":148,"value":"doseRemaining = (tHours, halflifeHours = HalfLifeHrs) => {\n if (tHours == 0) return 1.0;\n return 1 * Math.pow(0.5, (tHours - 1) / halflifeHours);\n}","pinned":true,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":1640,"value":"dosesToStreams = (dosesByHour, { totalHours, Bolus, infusion }) => {\n return Array.from(dosesByHour)\n .map(([startTime, cups]) => {\n startTime = parseInt(startTime);\n return d3.range(cups).map((i) => {\n const dose = Bolus;\n return [\n [startTime, 0],\n ...d3\n .range(startTime + 1, totalHours + 1)\n .map((t) => [t, (1 / 0.45) * dose * doseRemaining(t - startTime)])\n ];\n });\n })\n .flat();\n}","pinned":true,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":4931,"value":"infusionToStreams = (dosesByHour, { totalHours, infusion }) => {\n return Array.from(dosesByHour)\n .map(([startTime, cups]) => {\n startTime = parseInt(startTime);\n return d3.range(cups).map((i) => {\n const dose = infusion;\n return [\n [startTime, 0],\n ...d3.range(startTime + 1, totalHours + 1).map((t) => [t, dose])\n ];\n });\n })\n .flat();\n}","pinned":true,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":4260,"value":"state.infusion","pinned":true,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":1710,"value":"stackStreams = (streams) => {\n const amountsByHour = d3.rollup(\n streams.flat(),\n (ds) => ds.map(([t, v]) => v),\n (d) => d[0]\n );\n\n return streams.map((curStream, streamIndex) => {\n return curStream.map(([t, _]) => [\n t,\n d3.sum(amountsByHour.get(t).slice(0, streamIndex)),\n d3.sum(amountsByHour.get(t).slice(0, streamIndex + 1))\n ]);\n });\n}","pinned":false,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":728,"value":"md`## Charts & Inputter` ","pinned":false,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":525,"value":"$46","pinned":false,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":4155,"value":"$47","pinned":false,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":2436,"value":"renderGrid = () => {\n // return null\n\n return svg`\n\n${d3\n .range(100)\n .map(\n (i) =>\n svg``\n )}\n${d3\n .range(100)\n .map(\n (i) =>\n svg``\n )}\n\n`;\n}","pinned":false,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":1459,"value":"renderBolus = () => {\n return svg`💉`;\n}","pinned":false,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":1959,"value":"renderTargetIcon = () => {\n return svg`🧠`;\n}","pinned":false,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":1756,"value":"shakyStreamPlotFn = (data, params) => {\n const { x, y, margin, seriesIndex, colors } = params;\n\n const fillColor = colors[seriesIndex % colors.length];\n\n let classString = \"stream\";\n if (data.entered) {\n classString = classString + \" entered\";\n }\n // upsample the data to support the jitters\n data = upsample(data, [\"x\", \"y0\", \"y\"], 50);\n\n const shakeFactor = d3\n .scaleLinear()\n .domain([TargetThreshold, 100])\n .range([0, 1])\n .clamp(true);\n\n // Chosen for look\n const amplitude = 0.9;\n\n // Render with shakes\n const area = d3\n .area()\n .x((d, j) => x(d.x) + 1 * Math.cos(x(d.x) * amplitude) * shakeFactor(d.y))\n .y0(\n (d, j) => y(d.y0) + -1 * Math.cos(x(d.x) * amplitude) * shakeFactor(d.y0)\n )\n .y1(\n (d, j) => y(d.y) + -1 * Math.cos(x(d.x) * amplitude) * shakeFactor(d.y)\n );\n\n let output = svg`\n\n\n`;\n\n return output;\n}","pinned":false,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":1978,"value":"/**\n * Determine the earliest time the user could fall asleep\n * Uses global TargetThreshold\n */\ncalculatecalculateTime = (allData) => {\n if (0 === allData.length) return null;\n\n let calculateTime = 0;\n\n const calculateTimeCandidates = allData[allData.length - 1]\n .slice(1) // account for rampup hour\n .filter((d) => d.y > TargetThreshold);\n\n // Update the calculateTime based on the first candidate\n if (0 < calculateTimeCandidates.length) {\n // Not sure when a candidate might be below 0... is this old?\n calculateTime = Math.max(calculateTime, calculateTimeCandidates[0].x);\n }\n\n return calculateTime;\n}","pinned":false,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":2377,"value":"renderDayNightBar = () => {\n return svg`\n \n \n \n \n \n \n \n `;\n}","pinned":false,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":3275,"value":"rendertox_range_level = () => {\n return svg`\n \n \n \n \n \n \n \n `;\n}","pinned":false,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":3501,"value":"rendertherapeutic_range_level = () => {\n return svg`\n \n \n \n \n \n \n \n `;\n}","pinned":true,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":1768,"value":"sleeplinePlotFn = (allData, params) => {\n const { x, y, margin, seriesIndex, plotHeight, TargetThreshold } = params;\n\n if (allData.flat().filter((d) => TargetThreshold <= d.y).length === 0)\n return null;\n const calculateTime = calculatecalculateTime(allData);\n const output = svg`\n \n ${renderTargetIcon()}\n \n\n \n\n\n\n\n\n`;\n\n return output;\n}","pinned":false,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":1786,"value":"topCupsPlotFn = (allData, params) => {\n const { x, y, margin, seriesIndex } = params;\n\n const streamPeaks = allData.map((stream) => {\n return stream[d3.maxIndex(stream.map((d) => d.y))];\n });\n\n const streamPeaksByHour = d3.group(streamPeaks, (d) => d.x);\n\n const output = svg`\n ${Array.from(streamPeaksByHour).map(([k, streamPeaks]) => {\n const tallestPeakY = d3.max(streamPeaks.map((d) => d.y));\n\n return svg`\n ${streamPeaks.map((d, i) => {\n return svg`${renderBolus()}`;\n })}\n`;\n })}\n \n`;\n\n return output;\n}","pinned":false,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":1832,"value":"/**\n * Render columns of cups below the X-axis based on # of drinks\n */\ncupsPlotFn = (allData, params) => {\n const { x, y, margin, seriesIndex } = params;\n\n // Get the starting value for each stream, by hour\n const streamStarts = allData.map((stream) => stream[0]);\n const streamStartsByHour = d3.group(streamStarts, (d) => d.x);\n\n const output = svg`\n\n ${Array.from(streamStartsByHour).map(([k, streamStarts]) => {\n // At the start of each stream, render a stack of coffee cups\n return svg`\n \n ${streamStarts.map((d, i) => {\n return svg`\n \n ${renderBolus()}\n `;\n })}\n `;\n })}\n`;\n\n return output;\n}","pinned":false,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":1988,"value":"//parse / format an int into a time string e.g. \"6pm\"\nhourToTimeString = (x) =>\n d3.timeFormat(\"%-I%p\")(d3.timeParse(\"%I\")(x)).toLowerCase()","pinned":false,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":445,"value":"$48","pinned":false,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":2870,"value":"stackedAreaGraph = (data, params) => {\n data = stackStreams(\n data.map((curSeries) => curSeries.map((d) => [d.x, d.y]))\n ).map((curSeries) => curSeries.map(([x, y0, y]) => ({ x, y0, y })));\n\n const colors = [\"#4E4D93\", \"#4E4D93\", \"#4E4D93\"];\n\n return chart(data, {\n xTickFormatFn: (i) => i,\n plotFn: (data, params) => {\n let { x, y, margin, seriesIndex } = params;\n // colors = colors || []\n const fillColor = colors[seriesIndex % colors.length];\n\n const area = d3\n .area()\n .x((d, j) => x(d.x))\n .y0((d, j) => y(d.y0))\n .y1((d, j) => y(d.y));\n\n return svg`\n\n\n`;\n }\n });\n}","pinned":false,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":2,"value":"$49","pinned":false,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":788,"value":"md`## Includes`","pinned":false,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":8,"value":"\nd3 = require(\"d3@6\")","pinned":false,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":2159,"value":"import { slider, radio, select } from \"@jashkenas/inputs\"","pinned":true,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":2984,"value":"","pinned":false,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":4581,"value":"round = (n, places) => {\n if (!places) return Math.round(n);\n const d = 10 ** places;\n return Math.round(n * d) / d;\n}","pinned":true,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":4705,"value":"function set(input, value) {\n input.value = value;\n input.dispatchEvent(new Event(\"input\", { bubbles: true }));\n}","pinned":true,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"},{"id":3205,"value":"// viewof infusion = {\n// const output = slider({\n// title: \"Pentobarbital Infusion (mg/kg/hr)\",\n// min: 0.1,\n// max: 5,\n// step: 0.1,\n// value: state.infusion || 0\n// });\n// output.addEventListener(\"mouseup\", () => {\n// mutable state = { ...state, infusion: parseFloat(output.value) };\n// });\n// return output;\n// }\n","pinned":false,"hidden":false,"mode":"ojs","author":"$undefined","summary":"$undefined","tool":"$undefined","providerMetadata":"$undefined","attachments":"$undefined","output":"$undefined","database":"$undefined"}],"files":"$W4a","stdlib":"1"}} 44:"$43:body"