Here's a recent example on co-occurrence of Covid-19 symptoms: https://kieranhealy.org/blog/archives/2020/04/16/upset-plots/. I think this nicely highlights failures of Venn Diagrams, so could be useful in setting up clearer ways to visualize co-occurrence w/ more complex datasets. + I love a good UpSet plot.
I think it might be good to start the graph with a default filter, one that doesn't have so much overflow. (I also think there's ways we could tweak the simulation parameters to make this happen less.)