Published
Edited
Jan 11, 2021
1 star
md `# Papers
Bibliography attached in BibTex format (sc2-structure-function).
[The Impact of Mutations in SARS-CoV-2 Spike on Viral Infectivity and Antigenicity](https://www.sciencedirect.com/science/article/pii/S0092867420308771)
[Deep Mutational Scanning of SARS-CoV-2 Receptor Binding Domain Reveals Constraints on Folding and ACE2 Binding](Deep Mutational Scanning of SARS-CoV-2 Receptor Binding Domain Reveals Constraints on Folding and ACE2 Binding)
[Escape from neutralizing antibodies by SARS-CoV-2 spike protein variants](https://elifesciences.org/articles/61312)
[Genomic Mutations and Changes in Protein Secondary Structure and Solvent Accessibility of SARS-CoV-2 (COVID-19 Virus)](https://www.biorxiv.org/content/10.1101/2020.07.10.171769v1.abstract)
[Immunoinformatic Analysis of T- and B-Cell Epitopes for SARS-CoV-2 Vaccine Design](https://www.mdpi.com/2076-393X/8/3/355)
[Comparative genome analysis of novel coronavirus (SARS-CoV-2) from different geographical locations and the effect of mutations on major target proteins: An in silico insight](https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0238344)
[Analysis of the potential impact of genomic variants in global SARS-CoV-2 genomes on molecular diagnostic assays](https://www.sciencedirect.com/science/article/pii/S1201971220322906)
[Mutations Strengthened SARS-CoV-2 Infectivity](https://arxiv.org/abs/2005.14669)
[Tracking Changes in SARS-CoV-2 Spike: Evidence that D614G Increases Infectivity of the COVID-19 Virus](https://www.sciencedirect.com/science/article/pii/S0092867420308205)
[Mutations in the SARS-CoV-2 spike RBD are responsible for stronger ACE2 binding and poor anti-SARS-CoV mAbs cross-neutralization](https://www.sciencedirect.com/science/article/pii/S2001037020304694)
[Characterizing SARS-CoV-2 mutations in the United States](https://arxiv.org/abs/2007.12692)
[The circulating SARS-CoV-2 spike variant N439K maintains fitness while evading antibody-mediated immunity](https://www.biorxiv.org/content/10.1101/2020.11.04.355842v1.abstract)
[Structural Genetics of circulating variants affecting the SARS-CoV-2 Spike / human ACE2 complex](https://www.biorxiv.org/content/10.1101/2020.09.09.289074v1.abstract)
[Antibody cocktail to SARS-CoV-2 spike protein prevents rapid mutational escape seen with individual antibodies](https://science.sciencemag.org/content/369/6506/1014.abstract)
[Single point mutations can potentially enhance infectivity of SARS-CoV-2 revealed by in silico affinity maturation and SPR assay](https://www.biorxiv.org/content/10.1101/2020.12.24.424245v1.abstract)
[Key residues of the receptor binding motif in the spike protein of SARS-CoV-2 that interact with ACE2 and neutralizing antibodies](https://www.nature.com/articles/s41423-020-0458-z)
[Emergence of SARS-CoV-2 spike RBD mutants that enhance viral infectivity through increased human ACE2 receptor binding affinity](https://www.biorxiv.org/content/10.1101/2020.03.15.991844v5.full)
[Mutations in SARS-CoV-2 Leading to Antigenic Variations in Spike Protein: A Challenge in Vaccine Development](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7462717/)
`
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this.atomColor = function (atom) {
if (atom.chainname == 'A') {
// ACE2
return 0xFF0000 // red
}
if (s_mutations[''+(atom.resno-333)]) {
return 0xffA500 // orange
} else {
return 0x0000FF // blue
}
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})
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return {
"ALA": "A",
"CYS": "C",
"ASP": "D",
"GLU": "E",
"PHE": "F",
"GLY": "G",
"HIS": "H",
"ILE": "I",
"LYS": "K",
"LEU": "L",
"MET": "M",
"ASN": "N",
"PRO": "P",
"GLN": "Q",
"ARG": "R",
"SER": "S",
"THR": "T",
"VAL": "V",
"TRP": "W",
"TYR": "Y"
}
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"5": [
{
"Amino_Acid_Change": "F338L",
"Article": "The Impact of Mutations in SARS-CoV-2 Spike on Viral Infectivity and Antigenicity"
}
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"8": [
{
"Amino_Acid_Change": "V341I",
"Article": "The Impact of Mutations in SARS-CoV-2 Spike on Viral Infectivity and Antigenicity , Antibody cocktail to SARS-CoV-2 spike protein prevents rapid mutational escape seen with individual antibodies"
}
],
"11": [
{
"Amino_Acid_Change": "A344S",
"Article": "Mutations in SARS-CoV-2 Leading to Antigenic Variations in Spike Protein: A Challenge in Vaccine Development"
}
],
"13": [
{
"Amino_Acid_Change": "R346K",
"Article": "Escape from neutralizing antibodies by SARS-CoV-2 spike protein variants"
},
{
"Amino_Acid_Change": "R346L",
"Article": "Escape from neutralizing antibodies by SARS-CoV-2 spike protein variants"
},
{
"Amino_Acid_Change": "R346S",
"Article": "Escape from neutralizing antibodies by SARS-CoV-2 spike protein variants"
},
{
"Amino_Acid_Change": "R346S",
"Article": "Escape from neutralizing antibodies by SARS-CoV-2 spike protein variants"
}
],
"15": [
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"Amino_Acid_Change": "A348V",
"Article": "Mutations in SARS-CoV-2 Leading to Antigenic Variations in Spike Protein: A Challenge in Vaccine Development"
},
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"Amino_Acid_Change": "A348T",
"Article": "Antibody cocktail to SARS-CoV-2 spike protein prevents rapid mutational escape seen with individual antibodies"
}
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"21": [
{
"Amino_Acid_Change": "N354D",
"Article": "The Impact of Mutations in SARS-CoV-2 Spike on Viral Infectivity and Antigenicity , Antibody cocktail to SARS-CoV-2 spike protein prevents rapid mutational escape seen with individual antibodies"
}
],
"26": [
{
"Amino_Acid_Change": "S359N",
"Article": "Antibody cocktail to SARS-CoV-2 spike protein prevents rapid mutational escape seen with individual antibodies"
}
],
"31": [
{
"Amino_Acid_Change": "D364Y",
"Article": "The Impact of Mutations in SARS-CoV-2 Spike on Viral Infectivity and Antigenicity , Emergence of SARS-CoV-2 spike RBD mutants that enhance viral infectivity through increased human ACE2 receptor binding affinity"
}
],
"34": [
{
"Amino_Acid_Change": "V367F",
"Article": "Mutations Strengthened SARS-CoV-2 Infectivity , The Impact of Mutations in SARS-CoV-2 Spike on Viral Infectivity and Antigenicity , Mutations in SARS-CoV-2 Leading to Antigenic Variations in Spike Protein: A Challenge in Vaccine Development , Emergence of SARS-CoV-2 spike RBD mutants that enhance viral infectivity through increased human ACE2 receptor binding affinity"
}
],
"45": [
{
"Amino_Acid_Change": "K378R",
"Article": "Antibody cocktail to SARS-CoV-2 spike protein prevents rapid mutational escape seen with individual antibodies"
}
],
"53": [
{
"Amino_Acid_Change": "K386K",
"Article": "Analysis of the potential impact of genomic variants in global SARS-CoV-2 genomes on molecular diagnostic assays"
}
],
"58": [
{
"Amino_Acid_Change": "P391S",
"Article": "Identification of destabilizing SNPs in SARS-CoV2-ACE2 protein and spike glycoprotein: implications for virus entry mechanisms"
}
],
"75": [
{
"Amino_Acid_Change": "R408I",
"Article": "Comparative genome analysis of novel coronavirus (SARS-CoV-2) from different geographical locations and the effect of mutations on major target proteins: An in silico insight"
},
{
"Amino_Acid_Change": "R408I",
"Article": "Mutations in SARS-CoV-2 Leading to Antigenic Variations in Spike Protein: A Challenge in Vaccine Development , Comparative genome analysis of novel coronavirus (SARS-CoV-2) from different geographical locations and the effect of mutations on major target proteins: An in silico insight , Antibody cocktail to SARS-CoV-2 spike protein prevents rapid mutational escape seen with individual antibodies"
}
],
"76": [
{
"Amino_Acid_Change": "Q409E",
"Article": "Antibody cocktail to SARS-CoV-2 spike protein prevents rapid mutational escape seen with individual antibodies"
}
],
"81": [
{
"Amino_Acid_Change": "Q414E",
"Article": "The Impact of Mutations in SARS-CoV-2 Spike on Viral Infectivity and Antigenicity"
},
{
"Amino_Acid_Change": "Q414P",
"Article": "The Impact of Mutations in SARS-CoV-2 Spike on Viral Infectivity and Antigenicity"
}
],
"84": [
{
"Amino_Acid_Change": "V417L",
"Article": "Mutations in the SARS-CoV-2 spike RBD are responsible for stronger ACE2 binding and poor anti-SARS-CoV mAbs cross-neutralization"
},
{
"Amino_Acid_Change": "K417E",
"Article": "Antibody cocktail to SARS-CoV-2 spike protein prevents rapid mutational escape seen with individual antibodies"
}
],
"86": [
{
"Amino_Acid_Change": "A419S",
"Article": "Mutations in SARS-CoV-2 Leading to Antigenic Variations in Spike Protein: A Challenge in Vaccine Development"
}
],
"90": [
{
"Amino_Acid_Change": "Y423C",
"Article": "Mutations Strengthened SARS-CoV-2 Infectivity"
},
{
"Amino_Acid_Change": "Y423S",
"Article": "Mutations Strengthened SARS-CoV-2 Infectivity"
},
{
"Amino_Acid_Change": "Y423F",
"Article": "Mutations Strengthened SARS-CoV-2 Infectivity"
}
],
"101": [
{
"Amino_Acid_Change": "I434K",
"Article": "The Impact of Mutations in SARS-CoV-2 Spike on Viral Infectivity and Antigenicity"
}
],
"102": [
{
"Amino_Acid_Change": "A435S",
"Article": "Antibody cocktail to SARS-CoV-2 spike protein prevents rapid mutational escape seen with individual antibodies"
}
],
"103": [
{
"Amino_Acid_Change": "W436R",
"Article": "Emergence of SARS-CoV-2 spike RBD mutants that enhance viral infectivity through increased human ACE2 receptor binding affinity"
}
],
"105": [
{
"Amino_Acid_Change": "S438F",
"Article": "The Impact of Mutations in SARS-CoV-2 Spike on Viral Infectivity and Antigenicity"
}
],
"106": [
{
"Amino_Acid_Change": "N439K",
"Article": "Mutations Strengthened SARS-CoV-2 Infectivity , The Impact of Mutations in SARS-CoV-2 Spike on Viral Infectivity and Antigenicity , Escape from neutralizing antibodies by SARS-CoV-2 spike protein variants , Structural Genetics of circulating variants affecting the SARS-CoV-2 Spike / human ACE2 complex , The circulating SARS-CoV-2 spike variant N439K maintains fitness while evading antibody-mediated immunity"
},
{
"Amino_Acid_Change": "N439K",
"Article": "Mutations Strengthened SARS-CoV-2 Infectivity , The Impact of Mutations in SARS-CoV-2 Spike on Viral Infectivity and Antigenicity , Escape from neutralizing antibodies by SARS-CoV-2 spike protein variants , Structural Genetics of circulating variants affecting the SARS-CoV-2 Spike / human ACE2 complex , The circulating SARS-CoV-2 spike variant N439K maintains fitness while evading antibody-mediated immunity"
}
],
"107": [
{
"Amino_Acid_Change": "N440K",
"Article": "Escape from neutralizing antibodies by SARS-CoV-2 spike protein variants"
}
],
"111": [
{
"Amino_Acid_Change": "K444Q",
"Article": "Antibody cocktail to SARS-CoV-2 spike protein prevents rapid mutational escape seen with individual antibodies"
},
{
"Amino_Acid_Change": "K444N",
"Article": "Escape from neutralizing antibodies by SARS-CoV-2 spike protein variants"
}
],
"112": [
{
"Amino_Acid_Change": "V445A",
"Article": "Antibody cocktail to SARS-CoV-2 spike protein prevents rapid mutational escape seen with individual antibodies"
}
],
"113": [
{
"Amino_Acid_Change": "G446S",
"Article": "Immunoinformatic Analysis of T- and B-Cell Epitopes for SARS-CoV-2 Vaccine Design#Escape from neutralizing antibodies by SARS-CoV-2 spike protein variants"
},
{
"Amino_Acid_Change": "G446R",
"Article": "Immunoinformatic Analysis of T- and B-Cell Epitopes for SARS-CoV-2 Vaccine Design"
},
{
"Amino_Acid_Change": "G446C",
"Article": "Immunoinformatic Analysis of T- and B-Cell Epitopes for SARS-CoV-2 Vaccine Design"
},
{
"Amino_Acid_Change": "G446D",
"Article": "Immunoinformatic Analysis of T- and B-Cell Epitopes for SARS-CoV-2 Vaccine Design"
},
{
"Amino_Acid_Change": "G446V",
"Article": "Immunoinformatic Analysis of T- and B-Cell Epitopes for SARS-CoV-2 Vaccine Design#The Impact of Mutations in SARS-CoV-2 Spike on Viral Infectivity and Antigenicity#Escape from neutralizing antibodies by SARS-CoV-2 spike protein variants"
},
{
"Amino_Acid_Change": "G446A",
"Article": "Immunoinformatic Analysis of T- and B-Cell Epitopes for SARS-CoV-2 Vaccine Design"
}
],
"116": [
{
"Amino_Acid_Change": "Y449D",
"Article": "Immunoinformatic Analysis of T- and B-Cell Epitopes for SARS-CoV-2 Vaccine Design#Deep Mutational Scanning of SARS-CoV-2 Receptor Binding Domain Reveals Constraints on Folding and ACE2 Binding"
},
{
"Amino_Acid_Change": "Y449X",
"Article": "Immunoinformatic Analysis of T- and B-Cell Epitopes for SARS-CoV-2 Vaccine Design#Deep Mutational Scanning of SARS-CoV-2 Receptor Binding Domain Reveals Constraints on Folding and ACE2 Binding"
},
{
"Amino_Acid_Change": "Y449X",
"Article": "Immunoinformatic Analysis of T- and B-Cell Epitopes for SARS-CoV-2 Vaccine Design"
},
{
"Amino_Acid_Change": "Y449F",
"Article": "Immunoinformatic Analysis of T- and B-Cell Epitopes for SARS-CoV-2 Vaccine Design"
},
{
"Amino_Acid_Change": "Y449C",
"Article": "Immunoinformatic Analysis of T- and B-Cell Epitopes for SARS-CoV-2 Vaccine Design"
},
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"Amino_Acid_Change": "Y449H",
"Article": "Immunoinformatic Analysis of T- and B-Cell Epitopes for SARS-CoV-2 Vaccine Design#Deep Mutational Scanning of SARS-CoV-2 Receptor Binding Domain Reveals Constraints on Folding and ACE2 Binding"
}
],
"117": [
{
"Amino_Acid_Change": "N450D",
"Article": "Antibody cocktail to SARS-CoV-2 spike protein prevents rapid mutational escape seen with individual antibodies"
}
],
"119": [
{
"Amino_Acid_Change": "L452R",
"Article": "Mutations Strengthened SARS-CoV-2 Infectivity"
}
],
"120": [
{
"Amino_Acid_Change": "Y453F",
"Article": "Antibody cocktail to SARS-CoV-2 spike protein prevents rapid mutational escape seen with individual antibodies"
}
],
"122": [
{
"Amino_Acid_Change": "L455V",
"Article": "Deep Mutational Scanning of SARS-CoV-2 Receptor Binding Domain Reveals Constraints on Folding and ACE2 Binding , Key residues of the receptor binding motif in the spike protein of SARS-CoV-2 that interact with ACE2 and neutralizing antibodies"
},
{
"Amino_Acid_Change": "L455F",
"Article": "Deep Mutational Scanning of SARS-CoV-2 Receptor Binding Domain Reveals Constraints on Folding and ACE2 Binding , Key residues of the receptor binding motif in the spike protein of SARS-CoV-2 that interact with ACE2 and neutralizing antibodies"
},
{
"Amino_Acid_Change": "L455X",
"Article": "Deep Mutational Scanning of SARS-CoV-2 Receptor Binding Domain Reveals Constraints on Folding and ACE2 Binding , Key residues of the receptor binding motif in the spike protein of SARS-CoV-2 that interact with ACE2 and neutralizing antibodies"
},
{
"Amino_Acid_Change": "L455M",
"Article": "Deep Mutational Scanning of SARS-CoV-2 Receptor Binding Domain Reveals Constraints on Folding and ACE2 Binding , Key residues of the receptor binding motif in the spike protein of SARS-CoV-2 that interact with ACE2 and neutralizing antibodies"
},
{
"Amino_Acid_Change": "L455F",
"Article": "Deep Mutational Scanning of SARS-CoV-2 Receptor Binding Domain Reveals Constraints on Folding and ACE2 Binding , Key residues of the receptor binding motif in the spike protein of SARS-CoV-2 that interact with ACE2 and neutralizing antibodies"
}
],
"125": [
{
"Amino_Acid_Change": "K458N",
"Article": "The Impact of Mutations in SARS-CoV-2 Spike on Viral Infectivity and Antigenicity"
},
{
"Amino_Acid_Change": "K458R",
"Article": "Antibody cocktail to SARS-CoV-2 spike protein prevents rapid mutational escape seen with individual antibodies , The Impact of Mutations in SARS-CoV-2 Spike on Viral Infectivity and Antigenicity"
},
{
"Amino_Acid_Change": "K458N",
"Article": "The Impact of Mutations in SARS-CoV-2 Spike on Viral Infectivity and Antigenicity"
}
],
"134": [
{
"Amino_Acid_Change": "D467V",
"Article": "The Impact of Mutations in SARS-CoV-2 Spike on Viral Infectivity and Antigenicity"
}
],
"135": [
{
"Amino_Acid_Change": "I468F",
"Article": "The Impact of Mutations in SARS-CoV-2 Spike on Viral Infectivity and Antigenicity"
},
{
"Amino_Acid_Change": "I468T",
"Article": "The Impact of Mutations in SARS-CoV-2 Spike on Viral Infectivity and Antigenicity"
}
],
"139": [
{
"Amino_Acid_Change": "I472V",
"Article": "The Impact of Mutations in SARS-CoV-2 Spike on Viral Infectivity and Antigenicity , Antibody cocktail to SARS-CoV-2 spike protein prevents rapid mutational escape seen with individual antibodies"
}
],
"142": [
{
"Amino_Acid_Change": "A475V",
"Article": "The Impact of Mutations in SARS-CoV-2 Spike on Viral Infectivity and Antigenicity"
}
],
"143": [
{
"Amino_Acid_Change": "G476S",
"Article": "Mutations in SARS-CoV-2 Leading to Antigenic Variations in Spike Protein: A Challenge in Vaccine Development , Antibody cocktail to SARS-CoV-2 spike protein prevents rapid mutational escape seen with individual antibodies"
}
],
"144": [
{
"Amino_Acid_Change": "S477I",
"Article": "Structural Genetics of circulating variants affecting the SARS-CoV-2 Spike / human ACE2 complex"
},
{
"Amino_Acid_Change": "S477H",
"Article": "Single point mutations can potentially enhance infectivity of SARS-CoV-2 revealed by in silico affinity maturation and SPR assay"
},
{
"Amino_Acid_Change": "S477N",
"Article": "Mutations Strengthened SARS-CoV-2 Infectivity , Structural Genetics of circulating variants affecting the SARS-CoV-2 Spike / human ACE2 complex"
}
],
"145": [
{
"Amino_Acid_Change": "T478I",
"Article": "The Impact of Mutations in SARS-CoV-2 Spike on Viral Infectivity and Antigenicity"
}
],
"147": [
{
"Amino_Acid_Change": "D480G",
"Article": "Tracking Changes in SARS-CoV-2 Spike: Evidence that D614G Increases Infectivity of the COVID-19 Virus"
}
],
"150": [
{
"Amino_Acid_Change": "V483A",
"Article": "Mutations in SARS-CoV-2 Leading to Antigenic Variations in Spike Protein: A Challenge in Vaccine Development , Structural Genetics of circulating variants affecting the SARS-CoV-2 Spike / human ACE2 complex"
},
{
"Amino_Acid_Change": "V483I",
"Article": "The Impact of Mutations in SARS-CoV-2 Spike on Viral Infectivity and Antigenicity"
},
{
"Amino_Acid_Change": "V483A",
"Article": "Characterizing SARS-CoV-2 mutations in the United States , Mutations Strengthened SARS-CoV-2 Infectivity , Genomic Mutations and Changes in Protein Secondary Structure and Solvent Accessibility of SARS-CoV-2 (COVID-19 Virus) , Deep Mutational Scanning of SARS-CoV-2 Receptor Binding Domain Reveals Constraints on Folding and ACE2 Binding , Structural Genetics of circulating variants affecting the SARS-CoV-2 Spike / human ACE2 complex"
}
],
"151": [
{
"Amino_Acid_Change": "E484K",
"Article": "Escape from neutralizing antibodies by SARS-CoV-2 spike protein variants , Antibody cocktail to SARS-CoV-2 spike protein prevents rapid mutational escape seen with individual antibodies"
},
{
"Amino_Acid_Change": "E484D",
"Article": "Mutations Strengthened SARS-CoV-2 Infectivity"
}
],
"152": [
{
"Amino_Acid_Change": "G485D",
"Article": "Antibody cocktail to SARS-CoV-2 spike protein prevents rapid mutational escape seen with individual antibodies"
}
],
"153": [
{
"Amino_Acid_Change": "F486L",
"Article": "Genomic Mutations and Changes in Protein Secondary Structure and Solvent Accessibility of SARS-CoV-2 (COVID-19 Virus)#Deep Mutational Scanning of SARS-CoV-2 Receptor Binding Domain Reveals Constraints on Folding and ACE2 Binding"
},
{
"Amino_Acid_Change": "F486V",
"Article": "Deep Mutational Scanning of SARS-CoV-2 Receptor Binding Domain Reveals Constraints on Folding and ACE2 Binding"
},
{
"Amino_Acid_Change": "F486Y",
"Article": "Deep Mutational Scanning of SARS-CoV-2 Receptor Binding Domain Reveals Constraints on Folding and ACE2 Binding"
},
{
"Amino_Acid_Change": "F486L",
"Article": "Deep Mutational Scanning of SARS-CoV-2 Receptor Binding Domain Reveals Constraints on Folding and ACE2 Binding"
}
],
"156": [
{
"Amino_Acid_Change": "Y489W",
"Article": "Single point mutations can potentially enhance infectivity of SARS-CoV-2 revealed by in silico affinity maturation and SPR assay"
},
{
"Amino_Acid_Change": "Y489F",
"Article": "Mutations Strengthened SARS-CoV-2 Infectivity"
},
{
"Amino_Acid_Change": "Y489N",
"Article": "Mutations Strengthened SARS-CoV-2 Infectivity"
},
{
"Amino_Acid_Change": "Y489H",
"Article": "Mutations Strengthened SARS-CoV-2 Infectivity"
}
],
"157": [
{
"Amino_Acid_Change": "F490L",
"Article": "The Impact of Mutations in SARS-CoV-2 Spike on Viral Infectivity and Antigenicity"
},
{
"Amino_Acid_Change": "F490L",
"Article": "The Impact of Mutations in SARS-CoV-2 Spike on Viral Infectivity and Antigenicity"
},
{
"Amino_Acid_Change": "F490L",
"Article": "Escape from neutralizing antibodies by SARS-CoV-2 spike protein variants"
}
],
"158": [
{
"Amino_Acid_Change": "P491R",
"Article": "The Impact of Mutations in SARS-CoV-2 Spike on Viral Infectivity and Antigenicity"
}
],
"160": [
{
"Amino_Acid_Change": "Q493K",
"Article": "Antibody cocktail to SARS-CoV-2 spike protein prevents rapid mutational escape seen with individual antibodies"
},
{
"Amino_Acid_Change": "Q493H",
"Article": "Immunoinformatic Analysis of T- and B-Cell Epitopes for SARS-CoV-2 Vaccine Design"
},
{
"Amino_Acid_Change": "Q493M",
"Article": "Single point mutations can potentially enhance infectivity of SARS-CoV-2 revealed by in silico affinity maturation and SPR assay"
},
{
"Amino_Acid_Change": "Q493K",
"Article": "Immunoinformatic Analysis of T- and B-Cell Epitopes for SARS-CoV-2 Vaccine Design#Escape from neutralizing antibodies by SARS-CoV-2 spike protein variants , Antibody cocktail to SARS-CoV-2 spike protein prevents rapid mutational escape seen with individual antibodies"
},
{
"Amino_Acid_Change": "Q493E",
"Article": "Immunoinformatic Analysis of T- and B-Cell Epitopes for SARS-CoV-2 Vaccine Design"
},
{
"Amino_Acid_Change": "Q493P",
"Article": "Immunoinformatic Analysis of T- and B-Cell Epitopes for SARS-CoV-2 Vaccine Design"
},
{
"Amino_Acid_Change": "Q493R",
"Article": "Immunoinformatic Analysis of T- and B-Cell Epitopes for SARS-CoV-2 Vaccine Design , Escape from neutralizing antibodies by SARS-CoV-2 spike protein variants"
},
{
"Amino_Acid_Change": "Q493L",
"Article": "Immunoinformatic Analysis of T- and B-Cell Epitopes for SARS-CoV-2 Vaccine Design"
},
{
"Amino_Acid_Change": "Q493H",
"Article": "Immunoinformatic Analysis of T- and B-Cell Epitopes for SARS-CoV-2 Vaccine Design"
}
],
"161": [
{
"Amino_Acid_Change": "S494P",
"Article": "Escape from neutralizing antibodies by SARS-CoV-2 spike protein variants"
}
],
"163": [
{
"Amino_Acid_Change": "G496V",
"Article": "Immunoinformatic Analysis of T- and B-Cell Epitopes for SARS-CoV-2 Vaccine Design"
},
{
"Amino_Acid_Change": "G496A",
"Article": "Immunoinformatic Analysis of T- and B-Cell Epitopes for SARS-CoV-2 Vaccine Design"
},
{
"Amino_Acid_Change": "G496C",
"Article": "Immunoinformatic Analysis of T- and B-Cell Epitopes for SARS-CoV-2 Vaccine Design"
},
{
"Amino_Acid_Change": "G496R",
"Article": "Immunoinformatic Analysis of T- and B-Cell Epitopes for SARS-CoV-2 Vaccine Design"
},
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}
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